CLDN18.2

CLDN18.2 CAR-T Therapy Achieves 48-Month Disease Control and Conversion Surgery in Advanced Gastric Cancer With Peritoneal Metastasis

A remarkable case published in Journal of Hematology & Oncology highlights the potential of satricabtagene autoleucel (CT041), the world’s first approved solid tumor CAR-T therapy, in treating advanced gastric cancer with peritoneal metastasis. After receiving CT041 following first-line therapy, a 53-year-old patient achieved complete disappearance of peritoneal lesions, underwent successful conversion surgery, and maintained disease control for 48 months.

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Pancreatic Cancer

Pancreatic cancer is one of the most aggressive solid tumors with limited treatment success. CAR-T cell therapy in China is being actively researched as a new immunotherapy approach, offering potential hope through early-stage clinical trials and innovative engineered T-cell technologies.

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CLDN18.2: A New Beacon of Hope in Pancreatic Cancer Treatment

CLDN18.2 has become one of the most promising therapeutic targets in pancreatic cancer. From bispecific antibodies and antibody-drug conjugates to CAR-T cell therapy, researchers are exploring innovative approaches that could transform treatment options for patients with this difficult-to-treat disease.

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